Life Pro Healthy Evidenced Sleep is a product that contains prolonged-release melatonin, ashwagandha KSM-66, dry extract of lavender with linalool standardization as active ingredient, dry extract of passion flower with standardization of flavonoids as active ingredient, and dry extract of valerian.
Evidenced Sleep is a product formulated to improve both the quality of sleep and the time it takes us to fall asleep. Rest is essential for human health and, therefore, the components of Evidenced Sleep complement each other to form a puzzle of natural compounds that work in synergy to achieve a more restful and higher quality sleep.
The combination of prolonged-release melatonin , ashwagandha KSM-66, lavender, passion flower and valerian, generates a synergistic effect by modulating different neuronal pathways. In this way, Evidenced Sleep will generate two main effects. One will be the inhibition of pathways related to an increase in our arousal and activation, thus preventing our worries or other stimuli from keeping us active and alert, making it difficult to fall asleep and quality of sleep, as well as maintaining high levels of both stress and even depression. chronic anxiety. On the other hand, it will favor physiological pathways related to the reduction of neuronal activity and sleep conciliation. This will mean an improvement in our state of relaxation and well-being in those last hours of the day in which we need it, as well as a better quality of sleep and a shorter time needed to fall asleep. Although the compounds included in this product have scientifically demonstrated effects such as improving the quality of sleep, increasing relaxation, improving anxiety symptoms, improving stress symptoms or reducing cortisol levels (up to a 27.9%), the choice of raw materials has been key in each compound.
Insomnia is a fairly common sleep disorder and its prevalence increases with advancing years of life. The diagnosis is based on the patient's complaint of difficulty initiating or maintaining sleep and/or its quality (non-refreshing sleep), associated with drowsiness the next day, causing a negative impact on quality of life, falls and accidents. traffic. Currently, extended-release melatonin supplementation is a potential breakthrough treatment for primary insomnia. Unlike traditional melatonin (which is eliminated from the blood in less than an hour after taking it), slow-release or prolonged-release melatonin exerts its effects by mimicking the pattern of melatonin release that is generated in our body. In different studies, extended-release melatonin significantly improved participants' time to fall asleep, sleep quality, and morning alertness.
Ashwagandha with patent KSM-66 has been chosen because it is the patent with which it has been studied in science, demonstrating its effects in improving stress and anxiety, as well as reducing aforementioned cortisol. In addition, it significantly improves total sleep time and variables related to sleep quality. On the other hand, it also significantly improves aspects such as alertness after getting up or the time it takes us to fall asleep. Some of the main problems with ashwagandha extracts that are available on the market are their lack of standardization of their withanolide content, or the use of organic solvents during their production.
Therefore, the KSM-66® patent has been incorporated into this food supplement: the ashwagandha root extract most used in the scientific literature, and obtained in facilities that apply the principles of Good Manufacturing Practices through manufacturing processes. extraction that use water as a solvent, and not alcohol or other organic compounds. As a result of the production process, an extract is obtained that contains at least 5% withanolides determined by high-efficiency liquid chromatography, as well as a proportion of phytochemicals very close to that of the root, thanks to the fact that the processes of implemented extraction allow the retention of both hydrophilic and lipophilic compounds.
On the other hand, we offer a lavender extract standardized to an adequate % of linalool to guarantee that it is effective, having an anxiolytic effect and improving the quality of sleep. Multiple studies show that oral administration of lavender extracts significantly improves sleep quality and reduces anxiety levels both in healthy people and in different clinical populations. However, and as with ashwagandha, one of the most notable limitations in currently marketed lavender products is their lack of standardization in active ingredients such as linalool. For this reason, we have used for this product a dry extract of lavender with a standardized linalool content of 9%. It is the first lavender extract that has an effective dose and a correct % of standardized principle for use in capsules, so that taking it is easier. In addition, if we talk about passion flower, we have also made sure that its quintessential active principle, flavonoids, are present in effective doses to really generate the expected effect.
This is essential, since it is not enough for a product to have compounds with scientific evidence, but it must be ensured that the active principle that generates said effects is in the recommended dose. The same goes for valerian, which is correctly standardized to valeric acid. In this sense, valerian has been shown to reduce anxiety levels and improve sleep quality. Additionally, the scientific literature has reported more restful sleep reported by participants using valerian.
Finally, this product contains passion flower (Passiflora incarnata L.). Also popularly known as passion flower, this plant of the Passifloraceae family is made up of a wide variety of flavonoids, such as apigenin, luteolin, quercetin or campferol; and flavonoid glycosides, such as vitexin, isovitexin, orientin, and isoorientin, which could contribute to the anxiolytic effect of passionflower. The main mechanism of action is probably related to GABAergic neurotransmission, since some flavonoids such as apigenin show affinity for GABA receptors, which would mediate improved sleep and reduced anxiety levels after passion flower consumption. Consequently, supplementation with passion flower extract effectively reduces anxiety, and improves both the efficiency and latency time of sleep onset, so it may be useful for treating anxiety and sleep disorders.
Different components of this product, such as lavender, have comparative studies against renowned drugs from the benzodiazepine families, obtaining very positive and promising results in their effects, without the magnitude of side effects with which neither these drugs nor their dependence count. This is important due to the possible clinical repercussion.
Consume three capsules between 40 and 60 minutes before bedtime.
If you are currently taking pharmacological treatment to improve the symptoms of anxiety or stress, to improve reconciliation and quality of sleep, for depression or for any other purpose, consult your doctor before taking this product. Also, its use is not recommended during pregnancy.
Contenido
Investigador, entrenador y dietista. Graduado en ciencias de la actividad física y del deporte, máster en alto rendimiento deportivo, Dr. Internacional Cum Laude en ciencias del deporte aplicadas a las ayudas ergogénicas nutricionales, investigador internacional y docente universitario.
Graduado en ciencias de la actividad física y del deporte, máster en alto rendimiento deportivo, Dr. Internacional Cum Laude en ciencias del deporte aplicadas a la fisiología neuromuscular, investigador internacional y docente universitario.
